Study Complete
Sponsor ID
20050111

Pediatric Open-Label Extension Study of Etanercept in Patients with Plaque Psoriasis

Sponsor ID
20050111
Clinicaltrials.gov ID
NCT00141921
EUCTIS ID
N/A
EudraCT ID
N/A

Study Details

The purpose of this study is to evaluate the long-term safety and efficacy of etanercept in pediatric patients with moderate to severe psoriasis.

Additional Study Details

Phase
Phase 3
Product
etanercept
Type
Interventional
Masking
None (Open Label)
Enrollment
182
Additional Study Details

Protocol Summary

Primary Outcome Measures

Subject incidence of adverse events, including infectious episodes, serious adverse events, and serious infectious episodes

Timeframe: 168 Weeks

Secondary Outcome Measures

Injection site reactions

Timeframe: 168 Weeks

exposure adjusted event rates for adverse events

Timeframe: 168 Weeks

infections and injection site reactions

Timeframe: 168 weeks

physical examination

Timeframe: 168 weeks

vital signs

Timeframe: 168 weeks

laboratory toxicities

Timeframe: 168 weeks

anti-etanercept antibodies

Timeframe: 168 weeks

PASI 50

Timeframe: 168 weeks

PASI 75

Timeframe: 168 weeks

PASI 90

Timeframe: 168 weeks

Clear or almost clear status of sPGA

Timeframe: 168 weeks

percent improvement in CDLQI

Timeframe: 168 Weeks

improvement from baseline in joint pain

Timeframe: 168 weeks

Percent improvement in PASI score

Timeframe: 168 weeks

Study Documents

Study Synopsis
Available Language(s): English

Locations

No locations found.