Study Complete
Sponsor ID
20110132

Prospective Observational Study to Describe Characteristics and Management of Patients Treated With Denosumab (Prolia®) in Routine Clinical Practice

Sponsor ID
20110132
Clinicaltrials.gov ID
NCT01652690
EUCTIS ID
N/A
EudraCT ID
N/A

Study Details

The objective of this prospective, observational study in Czech Republic and Slovakia is to describe per country the characteristics of women treated with denosumab in routine clinical practice and the clinical management of these patients during the first 2 years of treatment. In addition, the study aims to collect safety data in the real-life clinical practice settings on adverse drug reactions (ADRs) and serious ADRs.

Additional Study Details

Phase
Phase 4
Product
denosumab
Type
Observational
Masking
N/A
Enrollment
600
Additional Study Details

Protocol Summary

Primary Outcome Measures

Incidence (yes/no) of patients receiving all prescriptions and injections of Prolia® from the initial prescribing physician’s office

Timeframe: 24 months from 1st Prolia® injection received

Incidence (yes/no) of patients receiving an individual prescription and injection of Prolia® from the initial prescribing physician office by each individual injection

Timeframe: 24 months from 1st Prolia® injection received

Incidence (yes/no) of patients receiving all prescriptions and injections of Prolia®, whether or not the injections are given at the initial prescribing physician’s office

Timeframe: 24 months from 1st Prolia® injection received

Incidence (yes/no) of patients with a referral by the prescribing physician to other health care providers for continuation or follow up of care by type of physician

Timeframe: 24 months from 1st Prolia® injection received

Types of health care providers administering an individual injection of Prolia® inside or outside the initial prescribing office by injection

Timeframe: 24 months from 1st Prolia® injection received

Number of Prolia® injections received by each patient during the follow-up period

Timeframe: 24 months from 1st Prolia® injection received

Incidence (yes/no) of patients having radiologic bone assessments pre-treatment with Prolia®, and during the study

Timeframe: 24 months from 1st Prolia® injection received

Incidence (yes/no) of patients having osteoporosis related laboratory examinations pre-treatment with Prolia®, and during the study.

Timeframe: 24 months from 1st Prolia® injection received

Secondary Outcome Measures

Incidence (yes/no) of patients with ADR to Prolia®.

Timeframe: 24 months from 1st Prolia® injection received

Incidence (yes/no) of patients with serious ADR to Prolia®.

Timeframe: 24 months from 1st Prolia® injection received

Study Documents

Study Synopsis
Available Language(s): English

Locations

Location
Status
Contact Us
Location
Osteocentrum Zlin
Zlin, Czech Republic
Status
Recruiting
Location
Research Site
Brno, Czech Republic, 602 00
Status
Recruiting
Location
Research Site
Praha 11, Czech Republic, 148 00
Status
Recruiting
Location
Research Site
Trutnov, Czech Republic, 541 21
Status
Recruiting
Location
Research Site
Zlin, Czech Republic, 760 01
Status
Recruiting
Location
Research Site
Ostrava-Trebovice, Czech Republic, 722 00
Status
Recruiting
Showing {first} - {last} of {total} Results