Study Complete
Sponsor ID
20180132
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of AMG 592 in Healthy Japanese Participants
Study Details
The primary objective of this study is to characterize the pharmacokinetics (PK) profile of a single dose of
AMG 592 administered subcutaneously in healthy Japanese participants.
Protocol Summary
Primary Outcome Measures
Maximum Observed Serum Concentration (Cmax) of AMG 592
Timeframe: Up to Day 43
Time of Maximum Observed Concentration (tmax) of AMG 592
Timeframe: Up to Day 43
Area Under the Serum Concentration-time Curve to the Last Measurable Point (AUClast) of AMG 592
Timeframe: Up to Day 43
Area Under the Concentration-time Curve (AUC) from Time Zero to Infinity (AUCinf)
Timeframe: Up to Day 43
Secondary Outcome Measures
Number of Participants who Experience Treatment-emergent Adverse Events (TEAEs)
Timeframe: Day 1 to Day 43
Number of Participants who Experience Anti-AMG 592 Antibodies Formation
Timeframe: Up to Day 43
Locations
Location
Research Site
Randwick, NSW, Australia, 2031
Status
Recruiting