Recruiting
Sponsor ID
20180442
A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease
Study Details
The primary objective of the study is to evaluate real-world effectiveness of treatment with Repatha® in combination with SOC, compared with SOC alone, on the risk for cardiovascular (CV) death, myocardial infarction (MI), stroke, hospitalization for unstable angina, or coronary revascularization, whichever occurs first, in participants with established atherosclerotic CV disease (ASCVD) treated with SOC, according to local clinical practice.
Protocol Summary
Primary Outcome Measures
Time to CV Death, MI, Hospitalization for Unstable Angina, Stroke, or Coronary Revascularization, Whichever Occurs First
Timeframe: Up to 72 months
Secondary Outcome Measures
Time to CV Death, MI, or Stroke, Whichever Occurs First
Timeframe: Up to 72 months
Change in Low-density Lipoprotein Cholesterol (LDL-C) From Baseline
Timeframe: Baseline and end of follow-up (up to 72 months)
Percent Change in LDL-C From Baseline
Timeframe: Baseline and end of follow-up (up to 72 months)
Number of Participants Who Experienced Adverse Events
Timeframe: Up to 72 months
Number of Participants Who Experienced Adverse Drug Reactions
Timeframe: Up to 72 months
Locations
Location
The First Affiliated Hospital of Shantou University Medical College
Guangzhou, Guangdong, China, 510280
Status
Recruiting
Location
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China, 330006
Status
Recruiting
Location
The First Peoples Hospital of Yunnan Province
Kunming, Yunnan, China, 650032
Status
Recruiting
Location
Tangshan Gongren Hospital
tangshan city, Hebei, China, 63000
Status
Recruiting
Location
Huaihe Hospital of Henan University
Kaifeng, Henan, China, 475000
Status
Recruiting
Location
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China, 221006
Status
Recruiting
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