Recruiting
Sponsor ID
20190531

A Study of Apremilast in Children With Oral Ulcers Associated With Behçet’s Disease or Juvenile Psoriatic Arthritis

Sponsor ID
20190531
Clinicaltrials.gov ID
NCT05767047
EUCTIS ID
2023-503433-21
EudraCT ID
2022-003024-41

Study Details

The primary objective of this study is to evaluate the long-term safety of apremilast in subjects 2 years of age or older with oral ulcers associated with Behçets disease or 5 years of age or older with active juvenile psoriatic arthritis that have completed Study 20190530 or Study 20190529.

Additional Study Details

Phase
Phase 3
Product
AMG 407
Type
Interventional
Masking
None (Open Label)
Enrollment
48
Additional Study Details

Protocol Summary

Primary Outcome Measures

Number of Participants with Adverse Events

Timeframe: Up to approximately 4 years

Columbia-Suicide Severity rating Scale (C-SSRS)

Timeframe: Up to approximately 4 years

Tanner Staging

Timeframe: Up to approximately 4 years

Change from Baseline in Body Weight

Timeframe: Up to approximately 4 years

Change from Baseline in Height

Timeframe: Up to approximately 4 years

Change from Baseline in Body Mass Index (BMI)

Timeframe: Up to approximately 4 years

Number of Participants with Clinically Significant Changes in Vital Signs

Timeframe: Up to approximately 4 years

Number of Participants with Clinically Significant Changes in Laboratory Parameters

Timeframe: Up to approximately 4 years

Secondary Outcome Measures
Not Available

Locations

Location
Status
Contact Us
Location
Hospital Universitari i Politecnic La Fe
Valencia, Comunidad Valenciana, Spain, 46026
Status
Recruiting
Location
Hospital Universitario Ramon y Cajal
Madrid, Madrid, Spain, 28034
Status
Recruiting
Location
Meir Medical Center
Kfar Saba, Israel, 4428164
Status
Recruiting
Location
General Hospital of Thessaloniki Ippokrateio
Thessaloniki, Greece, 54642
Status
Recruiting
Location
Istanbul Universitesi Cerrahpasa Tip Fakultesi
Istanbul, Turkey, 34098
Status
Recruiting
Location
Umraniye Egitim ve Arastirma Hastanesi
Istanbul, Turkey, 34764
Status
Recruiting
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