A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)ROCKET-Orbit

- Age ≥ 12 to < 18 years at day 1. - Participant has a diagnosis of AD (according to American Academy of Dermatology Consensus Criteria [Eichenfield, 2014]) that has been present for at least 12 months before signing of informed consent - Prior to informed consent, history of inadequate response to topical corticosteroids (TCS) of medium to higher potency (with or without topical calcineurin inhibitors [TCI] as appropriate) or for whom topical treatments are otherwise medically inadvisable (eg, because of important side effects or safety risks) - Eczema Area and Severity Index (EASI) score ≥ 12 - vIGA-AD score ≥ 3 - ≥ 10% BSA of AD involvement at day 1 pre-enrollment

- Treatment with a biological product within 12 weeks or 5 half-lives, whichever is longer, prior to Day 1 - Treatment with any of the following medications or therapies within 4 weeks or 5 half-lives, whichever is longer, prior to Day 1: • Systemic corticosteroids • Systemic immunosuppressants • Phototherapy • Oral or topical janus kinase inhibitors - Treatment with any of the following agents within 1 week before day 1 pre-enrollment: • Topical PDE4 inhibitors • Other topical immunosuppressive agents (not including TCS/TCI) • Combination topical agents containing a high- or super-high potency corticosteroid